Unintentional use of antibiotics is common and has serious consequences, primarily antibiotic resistance. Antibiotic-resistant infections are an important cause of morbidity and mortality, causing significant economic burden and a tangible danger to public health. 80-95% of antibiotic drugs are prescribed in the community. Due to the importance of this area, two quality indicators related to the volume of antibiotic drugs use in the community have been incorporated into QICH. The definitions of the indicators were adopted from the OECD in order to enable international comparisons: The total volume of use of systemic antibiotics in community medicine, and the proportion of second-line antibiotic drugs out of total antibiotic drugs used are measured.